Guanidine Hydrochloride
Guanidine hydrochloride, chemical title aminoformamidine hydrochloride, is a white or barely yellow block that is nearly insoluble in acetone, benzene, and ether. It can be used as an intermediate in the synthesis of pharmaceuticals, pesticides, dyes, and different machines. It is an vital uncooked fabric for manufacturing capsules such as sulfadiazine, sulfamethoxazole, sulfamethoxazole, and folic acid. It can additionally be used as an anti-static agent for artificial fibers.
Melting Point | 180-185 °C(lit.) |
Density | 1.18 g/mL at 25 °C(lit.) |
Refractivity | n20/D 1.465 |
Storage Conditions | room temp |
Solubility | H2O: 6 M, clear, colorless |
Form | Crystals |
Colour | White to slightly yellow |
Ph Value | 4.5-5.5 (100g/l, H2O, 20℃) |
1. It can be used as an intermediate in medicine, pesticides, dyes, and different natural synthesis. It can be used to synthesize 2-aminopyrimidine, 2-amino-6-methylpyrimidine, 2-amino-4,6-dimethylpyrimidine, and is an intermediate in the manufacturing of sulfonamide capsules such as sulfadiazine, sulfamethylpyrimidine, and sulfamethoxypyrimidine.
2. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to shape 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize the anti anemia drug folic acid. It can additionally be used as an anti-static agent for artificial fibers.