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Oseltamivir phosphate
Oseltamivir phosphate is a new kind of Neuraminidase (NA) inhibitor with excessive selectivity. It can be used for the therapy and prevention of influenza virus infection, bronchitis accompanying infection, pneumonia, systemic pain, and extreme fever, mainly for influenza A and B viruses. Oseltamivir used to be listed in Switzerland in 1999. A massive range of scientific practices have proved that oseltamivir has the blessings of excessive efficiency, low resistance, right affected person tolerance, and excessive safety. It is broadly used in the medical prevention and remedy of influenza.
| CAS NO | 204255-11-8 |
| Molecular formula | C16H31N2O8P |
| melting point | 196-198°C |
| solubility | H2O: soluble30mg/mL |
| form | powder |
| colour | white to beige |
| SOLUBLE | Soluble in water (75 mM) |
| optical activity | [α]/D -26 to -36°, c = 1 in H2O |
Pharmacological motion Oseltamivir phosphate is the drug precursor of its Active metabolite, and its Active metabolite (Oseltamivir Carboxylate) is a selective influenza virus Neuraminidase inhibitor. Neuraminidase is a glycoprotein on the floor of viruses. Its undertaking is fundamental for the launch of newly fashioned virus particles from contaminated cells and the similarly unfold of infectious viruses in the human body. The Active metabolite of this product can inhibit the Neuraminidase exercise of influenza A and Influenza B virus. In vitro, the 1/2 inhibitory awareness of virus Neuraminidase pastime was once as low as ng level. The Active metabolite was once determined to inhibit the boom of influenza virus in vitro, and its inhibition of replication and pathogenicity of influenza virus was once additionally found in vivo. This product reduces the unfold of influenza A or Influenza B virus by means of inhibiting the launch of virus from contaminated cells.
