Sugammadex sodium
Shugeng Glucose Sodium, additionally regarded as Bretin, is the world's first and solely unique binding neuromuscular blockade antagonist developed with the aid of MSD. It is a modified Cyclodextrin, which types a complicated with the neuromuscular blocking off capsules rocuronium or vecuronium in the plasma, thereby decreasing the variety of neuromuscular blocking off pills blended with nicotine receptors at the neuromuscular junction, thereby antagonizing the neuromuscular block brought about through rocuronium or vecuronium.
Purpose:
Shugeng Glucose Sodium is a selective Muscle relaxant, which is typically used for muscle spasticity and hypertonia. The drug has a tremendous effect.
Main function: Shugeng Glucose Sodium exerts this impact due to its γ- The molecular shape of Cyclodextrin can structure a complicated with rocuronium to minimize the free drug awareness in the blood, therefore reversing the neuromuscular blockading impact of rocuronium.
name | Sugammadex sodium |
CAS NO | 343306-79-6 |
Molecular formula | C72H104Na8O48S8 |
molecular weight | 2177.97 |
Storage conditions | Inert atmosphere,Room Temperature |
solubility | DMF: 2.5 mg/ml; DMSO: 2.5 mg/ml; DMSO:PBS (pH 7.2) (1:30): 0.03 mg/ml |
form | A crystalline solid |