Ulipristal Acetate

Ulinastatin acetate is a progesterone agonist/antagonist, and its mechanism of motion is to inhibit or extend ovulation; However, adjustments in the endometrium can also additionally be one of the motives for therapeutic effects. Ulinastatin acetate is a selective progesterone receptor modulator that has adverse and in part excitatory outcomes on progesterone receptors. It binds to the progesterone receptor in the human physique to forestall the binding of progesterone to the progesterone receptor. The efficacy of ulinastatin acetate relies upon on the time of administration at some point of the menstrual cycle. Administration at some stage in the metaphase of follicular hyperplasia can inhibit follicular formation and decrease estradiol concentration. Administration all through the height duration of luteinizing hormone can prolong follicular rupture for 5-9 days. Early luteal administration can't considerably lengthen endometrial maturation, however can limit endometrial thickness through 0.6 ± 2.2mm (mean ± SD).