Ropivacaine hydrochloride
Ropivacaine hydrochloride amide long-term neighborhood anesthetics. Its fats solubility is higher than that of Lidocaine and much less than that of Bupivacaine, and its anesthetic depth is eight instances that of Procaine. Due to its nearby anesthetic impact on the merchandise of liver metabolism, its impact is surprisingly long-lasting. Mainly used for regional block anesthesia and epidural anesthesia, for postoperative and shipping ache relief.
Epidural AdministrationofRopivacainehydrochloride monohydrate effectivelyblockneuroethicpain(bothmechanicalallodyniaandheathyperalgesia)withoutinductionfanalgesictoleranceandsignificantlydelaystheevelopment ofneuropathicpain producedbyperipheral nervenjury.Ropivacainehydrochloride inhibitionpressure-inducedincreasesinfiltrationcoefficient(Kf)withoutaffectingpulmonaryarterypressure (Ppa), Pulmonary capillary pressures(Ppc),andzonalcharacteristics(ZC).Ropivacaine hydrochloride monohydrate preventspressure-induced lungedemansociatedhyperpermeability yasevidencebymaintainingPaO2,lungwet-to-dryratioandplasma volumesinilartoshamrates.
name | Ropivacaine hydrochloride |
CAS NO | 132112-35-7 |
Molecular formula | C17H26N2O.ClH.H2O |
molecular weight | 328.88 |
melting point | 267-269°C |
Specific Rotation | D20 -7.28° (c = 2 in water) |
Storage conditions | 2-8°C |
solubility | H2O: soluble5mg/mL, clear |
form | powder |
colour | white to off-white |